ARA-290

Ara-290 is a synthetic peptide derived from the Erythropoietin (EPO) molecule, specifically engineered to target the innate repair receptor (IRR) without activating erythropoiesis. This decoupling enhances its potential in research applications focused on anti-inflammatory and cytoprotective effects in non-human test subjects. Ara-290 has been shown to modulate pro-inflammatory cytokines, thereby mitigating inflammatory cascades and promoting tissue repair mechanisms.
In laboratory settings, Ara-290 has demonstrated efficacy in models of neuropathic inflammation and microvascular dysfunction, making it a compelling candidate for studying mechanisms of tissue homeostasis and regeneration. Its ability to stabilize mitochondrial integrity and reduce oxidative stress further underscores its potential for advancing research into cellular resilience under pathological conditions.

Additionally, Ara-290’s short half-life and targeted receptor specificity provide a controlled framework for studying transient signaling pathways and receptor-ligand dynamics. Researchers value its non-erythropoietic profile for exploring therapeutic pathways without the confounding effects of hematopoietic stimulation, making it a highly specialized tool in peptide-based research.