KPV

KPV peptide, a tripeptide composed of lysine (Lys), proline (Pro), and valine (Val), is a synthetic derivative of alpha-melanocyte-stimulating hormone (α-MSH). In animal subjects, KPV exhibits potent anti-inflammatory and antimicrobial properties, making it a valuable focus in experimental research.

In laboratory settings, KPV has demonstrated the ability to modulate inflammatory cascades by inhibiting pro-inflammatory cytokine production, such as tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6), in test subjects. Additionally, it has been observed to influence microbiome dynamics due to its antimicrobial activity against pathogenic bacteria like Staphylococcus aureus.

Its interactions with melanocortin receptors, particularly MC1R, are hypothesized to drive its bioactivity, including oxidative stress modulation and cellular homeostasis in non-human test systems. The stability and efficacy of KPV under experimental conditions highlight its potential as a tool for understanding molecular pathways linked to inflammation and host-microbe interactions in controlled research environments. Its multifaceted properties make it a promising tool for studies on tissue repair and cellular regeneration in non-human research subjects.